化工社化工社 化学情報印刷レポート · 研究参考用
HRID 57550作成日：2026年10月24日
N-methyl-5-nitro-N-(tetrahydro-2H-pyran-4-yl)pyridin-2-amine → N2-methyl-N2-(tetrahydro-2H-pyran-4-yl)-2,5-Pyridinediamine
https://huagongshe.com/ja/reaction/57550
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | N-methyl-5-nitro-N-(tetrahydro-2H-pyran-4-yl)pyridin-2-amine | HCID 71113503 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | N2-methyl-N2-(tetrahydro-2H-pyran-4-yl)-2,5-Pyridinediamine | HCID 43610738 | — |
反応手順
To a solution of N-methyl-5-nitro-N-(tetrahydro-2H-pyran-4-yl)pyridin-2-amine (217 mg, 0.92 mmol) in MeOH (30 mL) was added Pd/C (0.5 g). The mixture was stirred for 3 hours at 20° C. under 1 atm. H2. The reaction was filtered and concentrated to give dark red oil. MS (m/z): 208 (M+H)+
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US09434726B2 |
|---|
| 出典データセット | uspto-grants-2016_09 |
|---|
| ORD ID | ord-3bdf9a7e1e4441f8bbbb21f22db9e522 |
|---|
| 出典メモ | uspto-grants-2016_09 |
|---|
