関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Dibenzylamine | HCID 7656 | — |
| 反応物 | N-(2,3-Epoxypropyl)phthalimide | HCID 21601 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 2-(3-(Dibenzylamino)-2-hydroxypropyl)isoindoline-1,3-dione | HCID 10408694 | 56.2% |
反応手順
A mixture of 2-(oxiran-2-ylmethyl)isoindoline-1,3-dione (4.06 g, 20.0 mmol) and dibenzylamine (5.0 g, 25.4 mmol) was stirred at 80° C. overnight. EtOH (50 mL) was added, and stirred at room temperature. The mixture was filtered to give white solid (4.5 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US09434726B2 |
|---|
| 出典データセット | uspto-grants-2016_09 |
|---|
| ORD ID | ord-b2a2f15a0b8848bb82600afc499c63de |
|---|
| 出典メモ | uspto-grants-2016_09 |
|---|
