Hydrochloric Acid → (S)-methyl 2-((2-aminobutyl)amino)-2-oxoacetate hydrochloride
反応式
[ClH:1].C(OC([NH:9][C@@H:10]([CH2:19][CH3:20])[CH2:11][NH:12][C:13](=[O:18])[C:14]([O:16][CH3:17])=[O:15])=O)(C)(C)C>O1CCOCC1>[ClH:1].[NH2:9][C@@H:10]([CH2:19][CH3:20])[CH2:11][NH:12][C:13](=[O:18])[C:14]([O:16][CH3:17])=[O:15]参加物
4
実験手順
To an ice cold solution of 4M HCl in dioxane (20 mL) was added (S)-methyl 2-((2-((tert-butoxycarbonyl)amino)butyl)amino)-2-oxoacetate (1.3 g, 4.6 mmol). After 30 minutes, the reaction mixture was concentrated to provide a yellow foam (968 mg, 100%), which was used without further purification. MS (ESI): mass calcd. for C7H14N2O3, 174.1; m/z found, 175.2 [M+H]+.
後処理
- concentrationthe reaction mixture was concentrated
出典と根拠
- ORDレコード
- ord-bda0854d96414bc7a4b7580f3d972256
- 出典データセット
- uspto-grants-2015_05
- 特許番号
- US09040534B2
反応ノート
読み込み中…