Dimethylformamide diethylacetal → Ethyl 3-(dimethylamino)-2-(4-(trifluoromethyl)phenyl)acrylate
反応式
[F:1][C:2]([F:16])([F:15])[C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:5][CH:4]=1.C(O[CH:20](OCC)[N:21]([CH3:23])[CH3:22])C>>[CH3:20][N:21]([CH3:23])[CH:22]=[C:9]([C:6]1[CH:5]=[CH:4][C:3]([C:2]([F:15])([F:16])[F:1])=[CH:8][CH:7]=1)[C:10]([O:12][CH2:13][CH3:14])=[O:11]参加物
3
実験手順
The title compound was prepared in a manner similar to Example Preparation 10 using ethyl 2-(4-(trifluoromethyl)phenyl)acetate and 1,1-diethoxy-N,N-dimethylmethanamine to give the title compound. 1H NMR (400 MHz, chloroform-d) δ ppm 1.21 (t, J=7.1 Hz, 3 H) 2.71 (s, 6 H) 4.14 (q, J=7.2 Hz, 2 H) 7.31 (d, J=7.8 Hz, 2 H) 7.53 (d, J=7.8 Hz, 2 H) 7.61 (s, 1 H).
出典と根拠
- ORDレコード
- ord-9293822b9eaf431294285c1d19541a36
- 出典データセット
- uspto-grants-2015_05
- 特許番号
- US09040522B2
反応ノート
読み込み中…