Acetic Acid → 2-Methoxy-4-(methylamino)-5-nitrophenol

HRID 579691ノート

反応式

HRID 579691 の反応式
[CH3:1][NH:2][C:3]1[CH:8]=[C:7]2[O:9][CH2:10][O:11][C:6]2=[CH:5][C:4]=1[N+:12]([O-:14])=[O:13].C[O-].[Na+].C(O)(=O)C>CO.O>[CH3:10][O:9][C:7]1[CH:8]=[C:3]([NH:2][CH3:1])[C:4]([N+:12]([O-:14])=[O:13])=[CH:5][C:6]=1[OH:11]

参加物

6

反応物 3

HCID 176Acetic AcidHCID 10942334Sodium MethoxideHCID 13742671N-methyl-6-nitro-1,3-dioxaindan-5-amine

生成物 1

HCID 137426772-Methoxy-4-(methylamino)-5-nitrophenol

試薬・触媒・溶媒 2

HCID 887Methanol溶媒2 回HCID 962Water溶媒

実験手順

A solution of 0.1 mol (19.6 g) of 2-methylamino-4,5-methylenedioxy-1-nitrobenzene, prepared according to Example 3, in 80 ml of a 30% strength solution of sodium methylate in methanol is brought for 15 minutes to the refluxing temperature of the methanol. The reaction medium is diluted with 500 ml of water. After the filtrate has been neutralized with acetic acid, the expected product precipitates.

後処理

  1. customthe expected product precipitates

出典と根拠

ORDレコード
ord-9264688154a34f7aa552f22b3eac3875
出典データセット
uspto-grants-1988_06
特許番号
US04749379

反応ノート

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