5-Chlorovaleryl chloride → HCID 13656413、化合物
反応式
[NH2:1][CH:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[CH2:6][S:5][C:4]2[CH:13]=[CH:14][CH:15]=[CH:16][C:3]1=2.[Cl:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22](Cl)=[O:23]>O1CCOCC1>[Cl:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22]([NH:1][CH:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[CH2:6][S:5][C:4]2[CH:13]=[CH:14][CH:15]=[CH:16][C:3]1=2)=[O:23]参加物
4
実験手順
A mixture of 8.8 g of 11-amino-6,11-dihydrodibenzo[b,e]thiepin, 6.0 g of 5-chlorovaleryl chloride and 100 ml of dioxane is heated with stirring under reflux for 15 hours. The solvent is distilled off under reduced pressure. The residue is recrystallized from ethanol to give 12.5 g of the title compound, m.p. 155°-156° C.
後処理
- temperatureis heated
- temperatureunder reflux for 15 hours
- distillationThe solvent is distilled off under reduced pressure
- customThe residue is recrystallized from ethanol
出典と根拠
- ORDレコード
- ord-803d42ff85124d48bb7b648bf79a6341
- 出典データセット
- uspto-grants-1988_06
- 特許番号
- US04749703
反応ノート
読み込み中…