化工社化工社 化学情報印刷レポート · 研究参考用
2-Heptylpropane-1,3-diol → 2-(2-Propylpyrimidin-5-yl)-5-heptyl-1,3,2-dioxaborinane
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Heptylpropane-1,3-diol | HCID 225556 | — |
| 反応物 | Dimethyl (2-propylpyrimidin-5-yl)boronate | HCID 20135158 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 2-(2-Propylpyrimidin-5-yl)-5-heptyl-1,3,2-dioxaborinane | HCID 20135179 | — |
反応手順
20 g of dimethoxy-(2-propylpyrimidin-5-yl)-borane (obtained from 2-propylpyrimidin-5-ylmagnesium chloride and trimethoxyborane) and 30 g of 2-hydroxymethylnonan-1-ol are heated at 100° for 12 hours, the methanol formed being removed continuously by distillation. When the reaction is complete, excess nonanol is removed under reduced pressure, and 2-(2-propylpyrimidin-5-yl)-5-heptyl-1,3,2-dioxaborinane is obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04751017 |
| 出典データセット | uspto-grants-1988_06 |
| ORD ID | ord-4f39590fba9848cb949bb0ec8707ee19 |
| 出典メモ | uspto-grants-1988_06 |