4-Nitrobenzaldehyde → p-Nitrobenzaldoxime

HRID 580083

反応式

HRID 580083 の反応式
[N+:1]([C:4]1[CH:11]=[CH:10][C:7]([CH:8]=O)=[CH:6][CH:5]=1)([O-:3])=[O:2].Cl.[NH2:13][OH:14].Cl>CO.O>[N+:1]([C:4]1[CH:11]=[CH:10][C:7]([CH:8]=[N:13][OH:14])=[CH:6][CH:5]=1)([O-:3])=[O:2]

参加物

5

反応物 2

HCID 5414-NitrobenzaldehydeHCID 22471726HCID 22471726、化合物

生成物 1

HCID 96339p-Nitrobenzaldoxime収率 96.3%

試薬・触媒・溶媒 2

HCID 887Methanol溶媒HCID 962Water溶媒2 回

反応条件

温度
30 °C

実験手順

453 g (3 mols) of p-nitrobenzaldehyde was dissolved in 1350 ml of methanol and then, an aqueous solution of 241 g (3.3 mols) of hydrochloric acid hydroxylamine hydrochloride in 300 ml of water was added dropwise over 30 minutes while maintaining the reaction temperature at 30° C. Thereafter, stirring was effected at the same temperature for two hours and the mixture was diluted with 2000 ml of water. White crystals deposited were filtered, washed with water and dried. 480 g of p-nitrobenzaldoxime was obtained (yield, 96.5%). M.P. 128° to 131° C.

後処理

  1. filtrationWhite crystals deposited were filtered
  2. washwashed with water
  3. customdried

出典と根拠

ORDレコード
ord-43e5868c1ad648ac86e21e30d1b2af03
出典データセット
uspto-grants-1988_06
特許番号
US04751328

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