Hydrochloric Acid → 3-(3-Diethylaminopropylamino)-5-aminoindazole dihydrochloride

HRID 580133ノート

反応式

HRID 580133 の反応式
[CH2:1]([N:3]([CH2:18][CH3:19])[CH2:4][CH2:5][CH2:6][NH:7][C:8]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]([NH2:17])[CH:15]=2)[NH:10][N:9]=1)[CH3:2].[ClH:20].C(OCC)C>C(O)C>[ClH:20].[ClH:20].[CH2:18]([N:3]([CH2:1][CH3:2])[CH2:4][CH2:5][CH2:6][NH:7][C:8]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]([NH2:17])[CH:15]=2)[NH:10][N:9]=1)[CH3:19]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 201357883-(3-Diethylaminopropylamino)-5-aminoindazole

生成物 1

HCID 201357873-(3-Diethylaminopropylamino)-5-aminoindazole dihydrochloride

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

In 15 ml of absolute ethyl alcohol was dissolved 0.6 g of 3-(3-diethylaminopropylamino)-5-aminoindazole, and into the solution was introduced dried hydrogen chloride gas under cooling with ice. To the solution was added anhydrous diethyl ether to separate crystals. Then the crystals were obtained by filtration and dried to give 3-(3-diethylaminopropylamino)-5-aminoindazole dihydrochloride having the following analytical value.

後処理

  1. temperatureunder cooling with ice
  2. customto separate crystals
  3. customThen the crystals were obtained by filtration
  4. customdried

出典と根拠

ORDレコード
ord-902ca7c6c17e40c084c74154228125c2
出典データセット
uspto-grants-1988_06
特許番号
US04751302

反応ノート

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