2-(1H-Indazol-3-yl)-1H-isoindole-1,3(2H)-dione → 1-(3-Dimethylaminobutyl)-3-aminoindazole
反応式
[CH2:1]([N:3]([CH2:18]C)[CH2:4][CH2:5][CH2:6][N:7]1[C:15]2[C:10](=[C:11](Cl)[CH:12]=[CH:13][CH:14]=2)[C:9]([NH2:17])=[N:8]1)C.[C:20]1(=O)N(C2C3C(=CC=CC=3)NN=2)C(=O)C2=CC=CC=C12.Br.CC(N(C)C)CCBr.C1(=O)N(C2C3C(=CC=CC=3Cl)NN=2)C(=O)C2=CC=CC=C12.Br.BrCCCN(CC)CC>>[CH3:18][N:3]([CH3:1])[CH:4]([CH3:20])[CH2:5][CH2:6][N:7]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]([NH2:17])=[N:8]1参加物
6
反応物 5
生成物 1
実験手順
The same procedures for preparing 1-(3-diethylaminopropyl)-3-amino-4-chloroindazole as described in Example 89 were repeated except that 8 g of 3-phthalimidoindazole and 8.6 g of (1-methyl-3-bromopropyl)dimethylamine hydrobromide were employed instead of the 3-phthalimido-4-chloroindazole and the 3-bromopropyldiethylamine hydrobromide, respectively. As a result, 9.2 g of 1-(3-dimethylaminobutyl)-3-aminoindazole was obtained.
出典と根拠
- ORDレコード
- ord-1c2a83ad19fb4c03b3593ca7211e2660
- 出典データセット
- uspto-grants-1988_06
- 特許番号
- US04751302
反応ノート
読み込み中…