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Water → 3-Bromo-4-dimethylaminobenzophenone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | 4-(Dimethylamino)benzophenone | HCID 10737 | — |
| 反応物 | Bromine | HCID 24408 | — |
| 反応物 | Sodium Bisulfite | HCID 23665763 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 溶媒 | Toluene water | HCID 22272177 | — |
| 生成物 | 3-Bromo-4-dimethylaminobenzophenone | HCID 20133924 | — |
反応手順
22.5 g (0.1 mol) of 4-dimethylaminobenzophenone were dissolved in 60 ml of acetic acid, and then a solution of 5.3 ml (0.105 mol) of bromine in 20 ml of acetic acid was added dropwise thereto over a period of one hour, while stirring. The mixture was then stirred for 30 minutes more, and some water and some sodium bisulfite for decolorization were added. The greasy substance thus obtained was shaken with toluene/water, the toluene phase was washed twice more with water and dried, and the toluene was distilled off in vacuo. Yield: 24.4 g (80% of theory); viscous oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04753934 |
| 出典データセット | uspto-grants-1988_06 |
| ORD ID | ord-7e7e096c21da4933824590331772f5b7 |
| 出典メモ | uspto-grants-1988_06 |