Water → 3-Bromo-4-dimethylaminobenzophenone

HRID 580613

反応式

HRID 580613 の反応式
[CH3:1][N:2]([CH3:17])[C:3]1[CH:16]=[CH:15][C:6]([C:7]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[O:8])=[CH:5][CH:4]=1.[Br:18]Br.O.S(=O)(O)[O-].[Na+]>C(O)(=O)C.C1(C)C=CC=CC=1.O>[Br:18][C:4]1[CH:5]=[C:6]([CH:15]=[CH:16][C:3]=1[N:2]([CH3:17])[CH3:1])[C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:8]

参加物

7

反応物 4

HCID 962WaterHCID 107374-(Dimethylamino)benzophenoneHCID 24408BromineHCID 23665763Sodium Bisulfite

生成物 1

HCID 201339243-Bromo-4-dimethylaminobenzophenone

試薬・触媒・溶媒 2

HCID 176Acetic Acid溶媒2 回HCID 22272177Toluene water溶媒

実験手順

22.5 g (0.1 mol) of 4-dimethylaminobenzophenone were dissolved in 60 ml of acetic acid, and then a solution of 5.3 ml (0.105 mol) of bromine in 20 ml of acetic acid was added dropwise thereto over a period of one hour, while stirring. The mixture was then stirred for 30 minutes more, and some water and some sodium bisulfite for decolorization were added. The greasy substance thus obtained was shaken with toluene/water, the toluene phase was washed twice more with water and dried, and the toluene was distilled off in vacuo. Yield: 24.4 g (80% of theory); viscous oil.

後処理

  1. stirringThe mixture was then stirred for 30 minutes more
  2. customThe greasy substance thus obtained
  3. washthe toluene phase was washed twice more with water
  4. customdried
  5. distillationthe toluene was distilled off in vacuo

出典と根拠

ORDレコード
ord-7e7e096c21da4933824590331772f5b7
出典データセット
uspto-grants-1988_06
特許番号
US04753934

関連ノート

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