Ammonia → 2-(4-Iodophenyl)acetamide

HRID 581000ノート

反応式

HRID 581000 の反応式
[NH3:1].[I:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10](Cl)=[O:11])=[CH:5][CH:4]=1>CCOCC>[I:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10]([NH2:1])=[O:11])=[CH:5][CH:4]=1

参加物

4

反応物 2

HCID 222AmmoniaHCID 13340573HCID 13340573、化合物

生成物 1

HCID 130308042-(4-Iodophenyl)acetamide

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

Concentrated aqueous ammonia (density, 0.88 g/cm3) was added to a solution of 4-iodophenylacetyl chloride (2.80 g) in ether (30 ml) and the mixture was stirred at ambient temperature for 15 minutes. The product, 4-iodophenylacetamide, was obtained as a colourless crystalline solid (2.36 g), m.p: 200-204° C.; NMR: 3.34(2H,s), 6.87(H,bs), 7.44(2H,bs), 7.04-7.68(4H,AB); m/z 262(M+H).

出典と根拠

ORDレコード
ord-740f718f85734f74811c2adfaa9cbaf9
出典データセット
uspto-grants-1999_07
特許番号
US05919793

反応ノート

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