3-(3-Nitrophenyl)pyridine → 3-(Pyridin-3-yl)aniline

HRID 581972ノート

反応式

HRID 581972 の反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[CH:8]=[C:9]([N+:13]([O-])=O)[CH:10]=[CH:11][CH:12]=2)[CH:2]=1>C(O)C.[Ni]>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[CH:8]=[C:9]([CH:10]=[CH:11][CH:12]=2)[NH2:13])[CH:2]=1

参加物

4

反応物 1

HCID 121813273-(3-Nitrophenyl)pyridine

生成物 1

HCID 4595213-(Pyridin-3-yl)aniline

試薬・触媒・溶媒 2

HCID 935Nickel触媒HCID 702Ethanol溶媒

実験手順

3-(3-pyridyl)-nitrobenzene (9.1 g, 45.5 mmol) in ethanol (125 ml) is hydrogenated at ambient pressure for 1.75 hours using Raney Nickel as the catalyst. Filtration of the resulting solution through celite followed by evaporation of solvent quantitatively yields 3-(3-pyridyl)aniline.

後処理

  1. filtrationFiltration of the resulting solution through celite
  2. customfollowed by evaporation of solvent quantitatively yields 3-(3-pyridyl)aniline

出典と根拠

ORDレコード
ord-e2c51de4f901493c8a5c8e21efe583c1
出典データセット
uspto-grants-1999_07
特許番号
US05922724

反応ノート

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