化工社化工社 化学情報印刷レポート · 研究参考用
Trifluoroacetic acid → 4-(Carboxymethyloxy)-4'-cyano-biphenyl
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Trifluoroacetic acid | HCID 6422 | — |
| 反応物 | Tert-butyl [(4'-cyanobiphenyl-4-yl)oxy]acetate | HCID 640094 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 4-(Carboxymethyloxy)-4'-cyano-biphenyl | HCID 43243100 | — |
反応手順
32.9 g of 4-(tert.butyloxycarbonylmethyloxy)-4'-cyano-biphenyl dissolved in 250 ml of methylene chloride is mixed slowly with 137 ml of trifluoroacetic acid. After stirring for 3 hours, the reaction mixture is evaporated to dryness and the solid residue is triturated with water.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05922763 |
| 出典データセット | uspto-grants-1999_07 |
| ORD ID | ord-4d9ef553cb9c45fc9547898ae79c4bce |
| 出典メモ | uspto-grants-1999_07 |