Ethanol → HCID 53793766、化合物

HRID 582272

反応式

HRID 582272 の反応式
[C:1]([O:5]CC)(=O)[CH:2]=[CH2:3].[Cl:8][C:9]1[CH:14]=[C:13]([Cl:15])[CH:12]=[CH:11][C:10]=1[NH:16][NH2:17].[O-]CC.[Na+].C(O)C>C1(C)C=CC=CC=1>[Cl:8][C:9]1[CH:14]=[C:13]([Cl:15])[CH:12]=[CH:11][C:10]=1[N:16]1[CH2:3][CH2:2][C:1](=[O:5])[NH:17]1

参加物

6

反応物 4

HCID 702EthanolHCID 8821Ethyl AcrylateHCID 408929(2,4-Dichlorophenyl)hydrazineHCID 2723922Sodium ethoxide

生成物 1

HCID 53793766HCID 53793766、化合物

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

105.0 g (1.05 mol) of ethyl acrylate is added dropwise to a mixture of 37.3 g (211 mmol) of 2,4-dichlorophenylhydrazine, 18.6 g (273 mmol) of sodium ethoxide, 150 ml of ethanol and 150 ml of toluene and the mixture is subsequently stirred for 1 hour. The reaction mixture is evaporated to 100 ml and the residue is taken up in water. The organic phase is separated off and extracted with 5% strength NaOH. The combined aqueous phases are adjusted to a pH of 6.5 and the solid formed is filtered off with suction, washed with water and dried under reduced pressure.

後処理

  1. customThe reaction mixture is evaporated to 100 ml
  2. customThe organic phase is separated off
  3. extractionextracted with 5% strength NaOH
  4. customthe solid formed
  5. filtrationis filtered off with suction
  6. washwashed with water
  7. customdried under reduced pressure

出典と根拠

ORDレコード
ord-34b2a9f17ced415e99b406e2c111f7af
出典データセット
uspto-grants-1999_07
特許番号
US05922886

関連ノート

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