Carbon Tetrachloride → Ethyl 3-bromo-6-methoxy-2-methylbenzoate
反応式
[CH3:1][C:2]1[C:7]([C:8]([O:10][CH2:11][CH3:12])=[O:9])=[C:6]([O:13][CH3:14])[CH:5]=[CH:4][CH:3]=1.[Br:15]Br.ClC(Cl)(Cl)Cl>O>[Br:15][C:3]1[CH:4]=[CH:5][C:6]([O:13][CH3:14])=[C:7]([C:2]=1[CH3:1])[C:8]([O:10][CH2:11][CH3:12])=[O:9]参加物
5
実験手順
A mixture of ethyl 6-methyl-2-methoxybenzoate (8.4 g, 43.2 mmol), bromine (6.9 g, 43.2 mmol) and tetrachloromethane (170 ml) is stirred at room temperature for 60 hours. The reaction mixture is poured into water and extracted with ethyl acetate. The organic phase is separated and concentrated. The crude product is obtained as a yellow oil, 10.3 g (87.% y) and is used without further purification.
後処理
- extractionextracted with ethyl acetate
- customThe organic phase is separated
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-b1a6c1867ea34f2692ef6cf0673d0db8
- 出典データセット
- uspto-grants-1999_07
- 特許番号
- US05922905
反応ノート
読み込み中…