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4-Aminopyrimidine → 2,2'-Dithiobis[N-4-pyrimidinyl benzamide]
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Aminopyrimidine | HCID 68958 | — |
| 反応物 | 2,2'-Dithiodibenzoyl chloride | HCID 88164 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 2,2'-Dithiobis[N-4-pyrimidinyl benzamide] | HCID 21584563 | 2% |
反応手順
This compound was prepared according to the general method of Example 90 using 2,2'-dithiobisbenzoyl chloride (3.00 g, 8.74 mmol) in 75 mL of dichloromethane and 4-aminopyrimidine (1.66 g, 17.5 mmol) in 14 mL of pyridine. The crude product was triturated with a hot mixture of acetonitrile and DMF, filtered, and recrystallized from water-DMF to yield 0.08 g of the title compound, mp 234-235° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05929114 |
| 出典データセット | uspto-grants-1999_07 |
| ORD ID | ord-d881a339e814445cb42d203e19111e87 |
| 出典メモ | uspto-grants-1999_07 |