関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | N-Iodosuccinimide | HCID 120273 | — |
| 反応物 | HCID 178418407 | HCID 178418407 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 2-n-Butyl-5-hydroxymethyl-4-iodoimidazole | HCID 14898547 | 95% |
反応手順
N-Iodosuccinimide (148.75 g, 0.661 mol) was added to a stirred solution of 2-n-butyl-4-hydroxymethylimidazole (100.78 g, 0.652 mol) in 500 ml of absolute ethanol. After 20 minutes the solution was heated to 40-45° C. for 45 minutes, diluted with 2.5 L of water, and chilled. The crystalline product which formed was collected by filtration, washed with water, and dried to give 1.74.5 g (95%) of crystals; mp 166-166.5° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05929249 |
|---|
| 出典データセット | uspto-grants-1999_07 |
|---|
| ORD ID | ord-963353a592144156a5b116c9d881bf3b |
|---|
| 出典メモ | uspto-grants-1999_07 |
|---|
