化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → 4-(2-Aminoethyloxy)benzoyl-2(S)-phenylsulfonylamino-beta-alanine-HCl
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 1,4-Dioxane | HCID 31275 | — |
| 反応物 | 4-[2-(N-BOC-Amino)ethyloxy]benzoyl-2(S)-phenylsulfonylamino-beta-alanine tert-butyl ester | HCID 10840664 | — |
| 生成物 | 4-(2-Aminoethyloxy)benzoyl-2(S)-phenylsulfonylamino-beta-alanine-HCl | HCID 86754335 | — |
反応手順
A suspension of 2-3 (105 mg, 0.19 mmol) in 6N HCl (5 mL) was treated with dioxane (5 mL) to effect a homogeneous solution. After stirring for 20 h at ambient temperature, the solvents were evaporated and the resulting residue azeotroped with toluene to afford 12-1 as a colorless solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05929120 |
| 出典データセット | uspto-grants-1999_07 |
| ORD ID | ord-3545c1a839b84107a6729d4bc39d022f |
| 出典メモ | uspto-grants-1999_07 |