Triethylamine → HCID 22342905、化合物

HRID 584169ノート

反応式

HRID 584169 の反応式
[CH3:1][S:2](Cl)(=[O:4])=[O:3].[N:6]1[CH:11]=[CH:10][CH:9]=[C:8](/[CH:12]=[CH:13]/[CH2:14][OH:15])[CH:7]=1.C(N(CC)CC)C>ClCCl>[CH3:1][S:2]([O:15][CH2:14]/[CH:13]=[CH:12]/[C:8]1[CH:7]=[N:6][CH:11]=[CH:10][CH:9]=1)(=[O:4])=[O:3]

参加物

5

反応物 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 5861913(2E)-3-(3-Pyridinyl)-2-propen-1-ol

生成物 1

HCID 22342905HCID 22342905、化合物

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

Methane sulfonyl chloride (0.22 ml) was added to a mixture of (E)-3-(3-pyridyl)-2-propen-1-ol (0.36 g) and triethylamine (0.74 ml) in dichloromethane (5 ml) under −10° C. After being stirred at the same temperature for 0.5 hour, the reaction mixture was washed with saturated sodium bicarbonate, dried over magnesium sulfate and evaporated under reduced pressure to give (E)-3-(3-pyridyl)-2-propen-1-yl methanesulfonate.

後処理

  1. washthe reaction mixture was washed with saturated sodium bicarbonate
  2. dry with materialdried over magnesium sulfate
  3. customevaporated under reduced pressure

出典と根拠

ORDレコード
ord-95247ec2591a44b78f54802f377e74da
出典データセット
uspto-grants-2005_08
特許番号
US06924278B2

反応ノート

読み込み中…