3-Bromo-4-ethylaniline → 3-Bromo-4-ethylphenol
反応式
[Br:1][C:2]1[CH:3]=[C:4](N)[CH:5]=[CH:6][C:7]=1[CH2:8][CH3:9].N([O-])=[O:12].[Na+]>>[Br:1][C:2]1[CH:3]=[C:4]([OH:12])[CH:5]=[CH:6][C:7]=1[CH2:8][CH3:9]参加物
3
実験手順
In a manner similar to that of Example 1(d), by reacting 27 g (135 mmol) of 3-bromo-4-ethylphenylamine with 11 g (162 mmol) of sodium nitrite, and after purification by chromatography on a column of silica eluted with a mixture of heptane and ethyl acetate (90/10), 13 g (49%) of the expected product are obtained in the form of a brown oil.
後処理
- customafter purification by chromatography on a column of silica
- washeluted with a mixture of heptane and ethyl acetate (90/10), 13 g (49%) of the expected product
- customare obtained in the form of a brown oil
出典と根拠
- ORDレコード
- ord-e01dc76730c741868cac98fbfe867c85
- 出典データセット
- uspto-grants-2005_08
- 特許番号
- US06924400B2
反応ノート
読み込み中…