(5-(Ethoxymethoxy)-2-ethylphenyl)boronic acid → 1-(5'-Ethoxymethoxy-2,2'-diethylbiphenyl-4-yl)propan-1-one
反応式
[CH2:1]([C:3]1[CH:8]=[CH:7][C:6]([O:9][CH2:10][O:11][CH2:12][CH3:13])=[CH:5][C:4]=1B(O)O)[CH3:2].FC(F)(F)S(O[C:23]1[CH:28]=[CH:27][C:26]([C:29](=[O:32])[CH2:30][CH3:31])=[CH:25][C:24]=1[CH2:33][CH3:34])(=O)=O>>[CH2:12]([O:11][CH2:10][O:9][C:6]1[CH:7]=[CH:8][C:3]([CH2:1][CH3:2])=[C:4]([C:23]2[CH:28]=[CH:27][C:26]([C:29](=[O:32])[CH2:30][CH3:31])=[CH:25][C:24]=2[CH2:33][CH3:34])[CH:5]=1)[CH3:13]参加物
3
実験手順
In a manner similar to that of Example 1(g), by reacting 2 g (8.9 mmol) of 2-ethyl-5-ethoxymethoxyphenylboronic acid with 2.1 g (6.9 mmol) of 2-ethyl-4-propionylphenyl 1,1,1-trifluoromethanesulfonate, a black oil is obtained, which is used without further purification for the rest of the synthesis.
後処理
- customa black oil is obtained
- customwhich is used without further purification for the rest of the synthesis