Triethyl phosphite → HCID 22345602、化合物

HRID 584316ノート

反応式

HRID 584316 の反応式
Br[CH2:2][C:3]1[CH:4]=[C:5]([C:13]([O:15][CH3:16])=[O:14])[C:6](=[CH:11][CH:12]=1)[C:7]([O:9][CH3:10])=[O:8].[P:17]([O:24]CC)([O:21][CH2:22][CH3:23])[O:18][CH2:19][CH3:20]>>[CH2:19]([O:18][P:17]([CH2:2][C:3]1[CH:4]=[C:5]([C:13]([O:15][CH3:16])=[O:14])[C:6](=[CH:11][CH:12]=1)[C:7]([O:9][CH3:10])=[O:8])([O:21][CH2:22][CH3:23])=[O:24])[CH3:20]

参加物

3

反応物 2

HCID 31215Triethyl phosphiteHCID 232556044-Bromomethylphthalic acid dimethyl ester

生成物 1

HCID 22345602HCID 22345602、化合物収率 77%

実験手順

65.7 g (229 mmol) of dimethyl 4-bromomethylphthalate are placed in 100 ml (583 mmol) of triethyl phosphite in a round-bottomed flask. The mixture is refluxed for 4 hours. The medium is then distilled to remove the triethyl phosphite. 60.7 g (77%) of the expected product are obtained in the form of a yellow oil.

後処理

  1. temperatureThe mixture is refluxed for 4 hours
  2. distillationThe medium is then distilled
  3. customto remove the triethyl phosphite

出典と根拠

ORDレコード
ord-882fe2343f184fa89fb70693cf45f850
出典データセット
uspto-grants-2005_08
特許番号
US06924400B2

反応ノート

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