化工社化工社 化学情報印刷レポート · 研究参考用
Methanol → 4-[2-(2-Furyl)-5-methyl-4-oxazolylmethoxy]-3-methoxybenzyl alcohol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | Water | HCID 962 | — |
| 反応物 | Sodium borohydride | HCID 4311764 | — |
| 反応物 | 4-[2-(2-Furyl)-5-methyl-4-oxazolylmethoxy]-3-methoxybenzaldehyde | HCID 22344630 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 4-[2-(2-Furyl)-5-methyl-4-oxazolylmethoxy]-3-methoxybenzyl alcohol | HCID 53770049 | 101.4% |
反応手順
Sodium borohydride (825 mg) was added to a solution of 4-[2-(2-furyl)-5-methyl-4-oxazolylmethoxy]-3-methoxybenzaldehyde (6.84 g) in tetrahydrofuran (50 ml)-methanol (50 ml) at 0° C. After stirring for 1 hour, the reaction mixture was poured into water to give 4-[2-(2-furyl)-5-methyl-4-oxazolylmethoxy]-3-methoxybenzyl alcohol (6.98 g, yield 92%) as crystals.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06924300B2 |
| 出典データセット | uspto-grants-2005_08 |
| ORD ID | ord-da1b6e65df5a40d6942dd5ec9d7c5de4 |
| 出典メモ | uspto-grants-2005_08 |