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Thionyl Chloride → 4-(4-Chloromethyl-2-methoxyphenoxymethyl)-5-methyl-2-phenyloxazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 3-Methoxy-4-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzyl alcohol | HCID 57315820 | — |
| 生成物 | 4-(4-Chloromethyl-2-methoxyphenoxymethyl)-5-methyl-2-phenyloxazole | HCID 22344609 | 126.4% |
反応手順
In substantially the same manner in Reference Example 94, 3-methoxy-4-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzyl alcohol (6.00 g) was reacted with thionyl chloride (1.58 g) to obtain 4-(4-chloromethyl-2-methoxyphenoxymethyl)-5-methyl-2-phenyloxazole (5.77 g, yield 91%) as crystals.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06924300B2 |
| 出典データセット | uspto-grants-2005_08 |
| ORD ID | ord-a41e1f546806444ba5c78adb1444abab |
| 出典メモ | uspto-grants-2005_08 |