Phosphorus oxychloride → 2,6,7-Trichloro-3-methylquinoxaline
反応式
O=P(Cl)(Cl)[Cl:3].[Cl:6][C:7]1[CH:8]=[C:9]2[C:14](=[CH:15][C:16]=1[Cl:17])[NH:13][C:12](=O)[C:11]([CH3:19])=[N:10]2>CN(C)C1C=CN=CC=1>[Cl:3][C:12]1[C:11]([CH3:19])=[N:10][C:9]2[C:14](=[CH:15][C:16]([Cl:17])=[C:7]([Cl:6])[CH:8]=2)[N:13]=1参加物
4
実験手順
POCl3 was added to 6,7-Dichloro-3-methyl-1H-quinoxalin-2-one (10 g, 44 mmol) and 4-dimethylaminopyridine (1 g) and the mixture was refluxed for 0.5 hours. After cooling, the mixture was poured onto ice (500 ml), filtered and washed with water to afford the title compound.
後処理
- temperaturethe mixture was refluxed for 0.5 hours
- temperatureAfter cooling
- additionthe mixture was poured onto ice (500 ml)
- filtrationfiltered
- washwashed with water
出典と根拠
- ORDレコード
- ord-aa24519db1d843c2a38169ddc639d1c3
- 出典データセット
- uspto-grants-2005_08
- 特許番号
- US06927214B1
反応ノート
読み込み中…