1-Ethynyl-4-fluorobenzene → 2-(4-Fluoro-phenylethynyl)-3,5-dimethyl-3H-imidazole-4-carboxylic acid ethyl ester

HRID 584698

反応式

HRID 584698 の反応式
[CH2:1]([O:3][C:4]([C:6]1[N:7]([CH3:13])[C:8](Br)=[N:9][C:10]=1[CH3:11])=[O:5])[CH3:2].[C:14]([C:16]1[CH:21]=[CH:20][C:19]([F:22])=[CH:18][CH:17]=1)#[CH:15]>>[CH2:1]([O:3][C:4]([C:6]1[N:7]([CH3:13])[C:8]([C:15]#[C:14][C:16]2[CH:21]=[CH:20][C:19]([F:22])=[CH:18][CH:17]=2)=[N:9][C:10]=1[CH3:11])=[O:5])[CH3:2]

参加物

3

反応物 2

HCID 5226271-Ethynyl-4-fluorobenzeneHCID 13897513ethyl 2-bromo-1,4-dimethyl-1H-imidazole-5-carboxylate

生成物 1

HCID 99219422-(4-Fluoro-phenylethynyl)-3,5-dimethyl-3H-imidazole-4-carboxylic acid ethyl ester

実験手順

The title compound, MS: m/e=286.8 (M+H+) was prepared in accordance with the general method of example 1b from 2-bromo-3,5-dimethyl-3H-imidazole-4-carboxylic acid ethyl ester and 1-ethynyl-4-fluorobenzene.

出典と根拠

ORDレコード
ord-739bf19215cc4e67a642cb8f2503f8f5
出典データセット
uspto-grants-2005_08
特許番号
US06927232B2

関連ノート

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