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2-Acetylbutyrolactone → 3-[1-(3-Mesityl-2-methylanilino)ethylidene]tetrahydro-2-furanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Acetylbutyrolactone | HCID 10601 | — |
| 反応物 | 3-Mesityl-2-methylaniline | HCID 22249538 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 3-[1-(3-Mesityl-2-methylanilino)ethylidene]tetrahydro-2-furanone | HCID 69583528 | 95.9% |
反応手順
A solution of 3-mesityl-2-methylaniline (5.0 g, 22 mmol) and α-acetyl-γ-butyrolactone (14.2 g, 0.11 mol) in ethanol (100 mL) was heated at reflux for three days. The mixture was evaporated, and the residue was purified by silica gel column chromatography (10% ethyl acetate/hexane), to give the title compound (7.08 g) as white crystals.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06927221B2 |
| 出典データセット | uspto-grants-2005_08 |
| ORD ID | ord-aa75fcc7501d4cd68fb8d5995ad2fc31 |
| 出典メモ | uspto-grants-2005_08 |