化工社化工社 化学情報印刷レポート · 研究参考用
3-Methoxybenzoic Acid → 1-(3-Methoxybenzoyl)-2-methyl-1,2,3,4-tetrahydro-4-quinolinol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Methoxybenzoic Acid | HCID 11461 | — |
| 反応物 | 1,2,3,4-Tetrahydro-2-methyl-4-quinolinol | HCID 147634 | — |
| 生成物 | 1-(3-Methoxybenzoyl)-2-methyl-1,2,3,4-tetrahydro-4-quinolinol | HCID 22339232 | 27% |
反応手順
Starting with 2-methyl-1,2,3,4-tetrahydro-4-quinolinol (3.00 g, 18.3 mmol) synthesized in the published manner and 3-methoxybenzoic acid (3.34 g, 22.0 mmol), the same procedure as shown in Reference Example 19 was repeated to give the titled compound (1.45 g, yield: 27%) as a white crystal. (cis:trans=1:1)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06930104B2 |
| 出典データセット | uspto-grants-2005_08 |
| ORD ID | ord-5b593778956443bd8eafd7c9b3e79dea |
| 出典メモ | uspto-grants-2005_08 |