化工社化工社 化学情報印刷レポート · 研究参考用
3,4-Dimethylbenzoic acid → 1-(3,4-Dimethylbenzoyl)-2-methyl-1,2,3,4-tetrahydro-4-quinolinol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3,4-Dimethylbenzoic acid | HCID 12073 | — |
| 反応物 | 1,2,3,4-Tetrahydro-2-methyl-4-quinolinol | HCID 147634 | — |
| 生成物 | 1-(3,4-Dimethylbenzoyl)-2-methyl-1,2,3,4-tetrahydro-4-quinolinol | HCID 22339291 | 62.5% |
反応手順
Starting with 2-methyl-1,2,3,4-tetrahydro-4-quinolinol (1.00 g, 6.12 mmol) synthesized in the published manner and 3,4-dimethylbenzoic acid (1.20 g, 7.96 mmol), the same procedure as shown in Reference Example 19 was repeated to give the titled compound (1.13 g, yield: 48%) as an oil. (cis:trans=1:1)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06930104B2 |
| 出典データセット | uspto-grants-2005_08 |
| ORD ID | ord-b438aaa24d5e473fab42bdf6165d050d |
| 出典メモ | uspto-grants-2005_08 |