(R)-2-(3-tert-butyl-ureido)-propionic acid → 1-tert-Butyl-3-((S)-2-{4-[(4aS,8aR)-4-(3,4-dimethoxy-phenyl)-1-oxo-4a,5,8,8a-tetrahydro-1H-phthalazin-2-yl]-piperidin-1-yl}-1-methyl-2-oxo-ethyl)-urea

反応式

[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2[C@@H:20]3[C@@H:15]([CH2:16][CH:17]=[CH:18][CH2:19]3)[C:14](=[O:21])[N:13]([CH:22]3[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]3)[N:12]=2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].[C:28]([NH:32][C:33](=[O:40])[NH:34][C@H:35]([CH3:39])[C:36](O)=[O:37])([CH3:31])([CH3:30])[CH3:29].C(OC(=O)NCCCC(N1CCC(N2N=C(C3C=CC(OC)=C(OC)C=3)[C@@H]3[C@@H](CC=CC3)C2=O)CC1)=O)(C)(C)C>>[C:28]([NH:32][C:33]([NH:34][C@@H:35]([CH3:39])[C:36]([N:25]1[CH2:26][CH2:27][CH:22]([N:13]2[N:12]=[C:11]([C:5]3[CH:6]=[CH:7][C:8]([O:9][CH3:10])=[C:3]([O:2][CH3:1])[CH:4]=3)[C@@H:20]3[C@@H:15]([CH2:16][CH:17]=[CH:18][CH2:19]3)[C:14]2=[O:21])[CH2:23][CH2:24]1)=[O:37])=[O:40])([CH3:31])([CH3:30])[CH3:29]