HCID 22337641、化合物 → HCID 22337569、化合物
反応式
[C:1]([O:4][C:5]1[N:6]=[CH:7][C:8]2[C:13]([CH:14]=1)=[C:12]([N+:15]([O-])=O)[CH:11]=[CH:10][CH:9]=2)(=[O:3])[CH3:2].[H][H]>O1CCOCC1.[Ni]>[C:1]([O:4][C:5]1[N:6]=[CH:7][C:8]2[C:13]([CH:14]=1)=[C:12]([NH2:15])[CH:11]=[CH:10][CH:9]=2)(=[O:3])[CH3:2]参加物
5
実験手順
5-Nitro-3-isoquinolinyl acetate (50 mg, 0.21 mmol) in 1,4-dioxane (20 mL) was treated with Raney-nickel powder (85 mg) and exposed to a hydrogen atmosphere via a balloon for 16 hours. The mixture was filtered through a plug of Celite and the filtrate was concentrated under reduced pressure to provide the title compound which was used without further purification.
後処理
- filtrationThe mixture was filtered through a plug of Celite
- concentrationthe filtrate was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-6030cf523eb1485b8d630bbd1dfbbf4a
- 出典データセット
- uspto-grants-2005_08
- 特許番号
- US06933311B2
反応ノート
読み込み中…