3,3,4-Trimethylpentan-1-ol → 3,3,4-Trimethylpentanal

HRID 586142ノート

反応式

HRID 586142 の反応式
[CH3:1][C:2]([CH3:9])([CH:6]([CH3:8])[CH3:7])[CH2:3][CH2:4][OH:5].[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>C(Cl)Cl>[CH3:1][C:2]([CH3:9])([CH:6]([CH3:8])[CH3:7])[CH2:3][CH:4]=[O:5]

参加物

4

反応物 2

HCID 124253343,3,4-Trimethylpentan-1-olHCID 178418287HCID 178418287、化合物

生成物 1

HCID 124253353,3,4-Trimethylpentanal

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

3,3,4-Trimethylpentanol (1 equiv) is dissolved in CH2Cl2. Pyridinium chlorochromate (1.5 equiv) is added and the resulting mixture is stirred at ambient temperature. The liquid is decanted and concentrated by rotary evaporation. The residue is triturated with 1 to 1 diethyl ether/hexane and mixture is filtered and the filtrate is washed with 1 N HCl. The organic layer is dried over Na2SO4, decanted and concentrated. The aldehyde is purified by fractional distillation to yield 3,3,4-trimethylpentanal.

後処理

  1. customThe liquid is decanted
  2. concentrationconcentrated by rotary evaporation
  3. customThe residue is triturated with 1 to 1 diethyl ether/hexane and mixture
  4. filtrationis filtered
  5. washthe filtrate is washed with 1 N HCl
  6. dry with materialThe organic layer is dried over Na2SO4
  7. customdecanted
  8. concentrationconcentrated
  9. distillationThe aldehyde is purified by fractional distillation

出典と根拠

ORDレコード
ord-c4d859fffe7a41c28f5913316149751e
出典データセット
uspto-grants-2005_08
特許番号
US06936606B2

反応ノート

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