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2-Aminothiazole → (2,6-Dimethyl-phenyl)-(6-pyridin-2-yl-imidazo[2,1-b]thiazol-5-yl)-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Aminothiazole | HCID 2155 | — |
| 反応物 | 2-Pyridinecarboxaldehyde | HCID 14273 | — |
| 反応物 | 2,6-Dimethylphenyl isocyanide | HCID 76009 | — |
| 溶媒 | Perchloric Acid | HCID 24247 | — |
| 生成物 | (2,6-Dimethyl-phenyl)-(6-pyridin-2-yl-imidazo[2,1-b]thiazol-5-yl)-amine | HCID 7299211 | — |
反応手順
Compound 19 was prepared in accordance with the general synthesis instructions from 1.0 ml (0.1 mmol) 2-aminothiazole solution (0.1 M, MC), 0.575 ml (0.115 mmol) 2,6-dimethylphenylisonitrile solution (0.2 M, MC), 0.500 ml (0.15 mmol) 2-pyridinecarbaldehyde solution (0.3 M, MC) and 10 μl perchloric acid (w=20%) in a substance library.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06936631B2 |
| 出典データセット | uspto-grants-2005_08 |
| ORD ID | ord-0dd8bbf4d598414cb5aab664196add01 |
| 出典メモ | uspto-grants-2005_08 |