化工社化工社 化学情報印刷レポート · 研究参考用
4-tert-Butylbenzaldehyde → Butyl-[6-(4-tert-butyl-phenyl)-2-methyl-imidazo[2,1-b]thiazol-5-yl]-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-tert-Butylbenzaldehyde | HCID 70324 | — |
| 反応物 | Butyl isocyanide | HCID 76008 | — |
| 反応物 | 2-Amino-5-methylthiazole | HCID 351770 | — |
| 溶媒 | Perchloric Acid | HCID 24247 | — |
| 生成物 | Butyl-[6-(4-tert-butyl-phenyl)-2-methyl-imidazo[2,1-b]thiazol-5-yl]-amine | HCID 22335555 | — |
反応手順
Compound 42 was prepared in accordance with the general synthesis instructions from 1.0 ml (0.1 mmol) 5-methyl-thiazol-2-yl-amine solution (0.1 M, MC), 0.575 ml (0.115 mmol) n-butylisonitrile solution (0.2 M, MC), 0.500 ml (0.15 mmol) 4-tert-butylbenzaldehyde solution (0.3 M, MC) and 10 μl perchloric acid (w 20%) in a substance library.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06936631B2 |
| 出典データセット | uspto-grants-2005_08 |
| ORD ID | ord-122b565e01b840afae44d32172625f52 |
| 出典メモ | uspto-grants-2005_08 |