Potassium Carbonate → N-[4-[[N-methyl-N-(tetrahydropyran-4-yl)amino]methyl]phenyl]-7-(4-morpholinophenyl)-1-propyl-2,3-dihydro-1-benzazepine-4-carboxamide

反応式

B([O-])([O-])O[C:3]1[CH:8]=[CH:7][C:6]([N:9]2[CH2:14][CH2:13][O:12][CH2:11][CH2:10]2)=[CH:5][CH:4]=1.Br[C:18]1[CH:19]=[CH:20][C:21]2[N:27]([CH2:28][CH2:29][CH3:30])[CH2:26][CH2:25][C:24]([C:31]([NH:33][C:34]3[CH:39]=[CH:38][C:37]([CH2:40][N:41]([CH3:48])[CH:42]4[CH2:47][CH2:46][O:45][CH2:44][CH2:43]4)=[CH:36][CH:35]=3)=[O:32])=[CH:23][C:22]=2[CH:49]=1.C(=O)([O-])[O-].[K+].[K+]>O.C(OCC)(=O)C.C1C=CC([P]([Pd]([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1>[CH3:48][N:41]([CH2:40][C:37]1[CH:36]=[CH:35][C:34]([NH:33][C:31]([C:24]2[CH2:25][CH2:26][N:27]([CH2:28][CH2:29][CH3:30])[C:21]3[CH:20]=[CH:19][C:18]([C:3]4[CH:8]=[CH:7][C:6]([N:9]5[CH2:14][CH2:13][O:12][CH2:11][CH2:10]5)=[CH:5][CH:4]=4)=[CH:49][C:22]=3[CH:23]=2)=[O:32])=[CH:39][CH:38]=1)[CH:42]1[CH2:43][CH2:44][O:45][CH2:46][CH2:47]1