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Ammonia → 2-[4-[(2-amino-5-butoxy-4-iminocyclohexa-2,5-dien-1-ylidene)amino]-N-(2-hydroxyethyl)anilino]ethanol

HRID 587101
ノート
印刷プレビュー

反応式

HRID 587101 の反応式
Cl.[CH2:2]([N:4](C(C)C)[C:5]1[CH:10]=[CH:9][C:8]([NH2:11])=[CH:7][CH:6]=1)[CH3:3].Cl.Cl.[CH2:17]([O:21][C:22]1[CH:27]=[CH:26][C:25]([NH2:28])=[CH:24][C:23]=1[NH2:29])[CH2:18][CH2:19][CH3:20].N.[OH:31]O.[CH2:33]([OH:35])[CH3:34]>O>[NH2:28][C:25]1[C:26](=[N:11][C:8]2[CH:9]=[CH:10][C:5]([N:4]([CH2:2][CH2:3][OH:31])[CH2:34][CH2:33][OH:35])=[CH:6][CH:7]=2)[CH:27]=[C:22]([O:21][CH2:17][CH2:18][CH2:19][CH3:20])[C:23](=[NH:29])[CH:24]=1
参加物実験手順後処理出典と根拠反応ノート

参加物

7

反応物 5

HCID 222AmmoniaHCID 702EthanolHCID 784Hydrogen PeroxideHCID 1536941,3-Benzenediamine, 4-butoxy-, dihydrochlorideHCID 16211123N-Ethyl-N-isopropyl-p-phenylenediamine hydrochloride

生成物 1

HCID 1406628362-[4-[(2-amino-5-butoxy-4-iminocyclohexa-2,5-dien-1-ylidene)amino]-N-(2-hydroxyethyl)anilino]ethanol

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

To a solution of 0.925 g (0.003 mol) of N-ethyl-N-isopropyl-4-aminoaniline hydrochloride and 0.76 g (0.003 mol) of 4-butoxybenzene-1,3-diamine dihydrochloride in 2 ml of water and 6 ml of ethanol, brought to pH 9.5 with 20% aqueous ammonia, are added 10.2 ml of 6% aqueous hydrogen peroxide solution. After stirring for 24 hours at room temperature, the ethanol is removed and the coupling product formed is extracted with butanol. After removal of the butanol under vacuum, the gummy residue is taken up in ethyl acetate and then in ether. 0.470 g of 2-[[4-(2-amino-5-butoxy-4-iminocyclohexa-2,5-dienylideneamino)phenyl](2-hydroxyethyl)amino]ethanol 10 is obtained in the form of a blue-black powder after drying.

後処理

  1. customthe ethanol is removed
  2. customthe coupling product formed
  3. extractionis extracted with butanol
  4. customAfter removal of the butanol under vacuum

出典と根拠

ORDレコード
ord-00d1f0ebe0fa4bef90831e3d948b2145
出典データセット
uspto-grants-2016_01
DOI
10.6084/m9.figshare.5104873.v1
特許番号
US09226883B2

反応ノート

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