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tert-butyl N-((piperidin-2-yl)methyl)carbamate → Tert-butyl [(1-(4-((3-(sulfamoylmethyl)phenyl)amino)-1,3,5-triazin-2-yl)piperidine-2-yl)methyl]carbamate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | tert-butyl N-((piperidin-2-yl)methyl)carbamate | HCID 2756031 | — |
| 反応物 | rac-3-[(4-(2-Methoxymethylpiperidin-1-yl)-1,3,5-triazin-2-yl)amino]-benzenemethanesulfonamide | HCID 60197106 | — |
| 反応物 | 3-[(4-Chloro-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide | HCID 86679822 | — |
| 生成物 | Tert-butyl [(1-(4-((3-(sulfamoylmethyl)phenyl)amino)-1,3,5-triazin-2-yl)piperidine-2-yl)methyl]carbamate | HCID 60197197 | — |
反応手順
B7 was prepared following the procedure reported for B4 using A1 and rac-tert-butyl (piperidin-2-yl)methylcarbamate and obtained as a white crystalline solid; yield: 280 mg (65%). MS (ES) C21H31N7O4S requires: 477. found: 478 (M+H)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09226929B2 |
| 出典データセット | uspto-grants-2016_01 |
| ORD ID | ord-f379f6e7cd824fd297cc9dee8346742e |
| 出典メモ | uspto-grants-2016_01 |