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HRID 587144作成日：2026年10月25日

Dimethyl-(2-piperidin-2-yl-ethyl)-amine → rac-3-[(4-(2-(2-(Dimethylamino)ethyl)piperidin-1-yl)-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide

https://huagongshe.com/reaction/587144

反応式

関与物質

役割名称HCID仕込み量
反応物Dimethyl-(2-piperidin-2-yl-ethyl)-amineHCID 296295—
反応物rac-3-[(4-(2-Methoxymethylpiperidin-1-yl)-1,3,5-triazin-2-yl)amino]-benzenemethanesulfonamideHCID 60197106—
反応物3-[(4-Chloro-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamideHCID 86679822—
生成物rac-3-[(4-(2-(2-(Dimethylamino)ethyl)piperidin-1-yl)-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamideHCID 60197198—

反応手順

B8 was prepared following the procedure reported for B4 using A1 and rac-2-(2-(dimethylamino)ethyl)piperidine and obtained as a white crystalline solid; yield: 230 mg (61%). MS (ES) C19H29N7O2S requires: 419. found: 420 (M+H)+.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US09226929B2
出典データセットuspto-grants-2016_01
ORD IDord-3db4b5041afa430ca6e166688b695d9f
出典メモuspto-grants-2016_01