3-(4-methoxyphenyl)benzenesulfonyl Chloride → HCID 178488590、化合物

反応式

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:10]=[C:11]([S:15](Cl)(=[O:17])=[O:16])[CH:12]=[CH:13][CH:14]=2)=[CH:5][CH:4]=1.[NH2:19][C:20]1[CH:21]=[C:22]([C:26]2[NH:30][N:29]=[N:28][N:27]=2)[CH:23]=[CH:24][CH:25]=1>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([S:15]([NH:19][C:20]3[CH:25]=[CH:24][CH:23]=[C:22]([C:26]4[NH:30][N:29]=[N:28][N:27]=4)[CH:21]=3)(=[O:17])=[O:16])[CH:10]=2)=[CH:5][CH:4]=1

参加物

反応物 2

HCID 49887373-(4-methoxyphenyl)benzenesulfonyl Chloride

HCID 178507542HCID 178507542、化合物

生成物 1

HCID 178488590HCID 178488590、化合物収率 60%

実験手順

The product was prepared according to General Procedure 1, described in Example 1, starting from [3-(4-methoxyphenyl)phenyl]sulfonyl chloride (16 mg, 0.055 mmol) and 5-(3-aminophenyl)tetrazole (8 mg, 0.05 mmol) giving 12 mg (60%) of the title compound. MS (ESI+) calcd for C20H17N5O3S 407.10521, found 407.10532.

後処理

customThe product was prepared

出典と根拠

ORDレコード: ord-fd5a27487f514d8391143619491a97cd
出典データセット: uspto-grants-2016_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09233946B2

反応ノート

読み込み中…