HCID 70855554、化合物 → HCID 73554824、化合物
反応式
[Br:1][C:2]1[C:3]2[C:12]([CH3:13])=[CH:11][CH:10]=[CH:9][C:4]=2[S:5][C:6]=1[CH2:7][OH:8]>ClCCl.[O-2].[O-2].[Mn+4]>[Br:1][C:2]1[C:3]2[C:12]([CH3:13])=[CH:11][CH:10]=[CH:9][C:4]=2[S:5][C:6]=1[CH:7]=[O:8]参加物
4
実験手順
At room temperature, a solution of (3-bromo-4-methyl-benzo[b]thiophen-2-yl)-methanol (23d) (400 mg, 1.55 mmol) and manganese dioxide (652 mg, 7.5 mmol) in dichloromethane (20 mL) was stirred for 2 hours. The mixture was then filtered and evaporated under reduced pressure to afford the desired aldehyde (23e) as a white solid without further purification (310 mg, 1.21 mmol, 78%).
後処理
- filtrationThe mixture was then filtered
- customevaporated under reduced pressure
出典と根拠
- ORDレコード
- ord-84fb353d93e44d9c8abed026e87bf638
- 出典データセット
- uspto-grants-2016_01
- 特許番号
- US09238026B2
反応ノート
読み込み中…