Chlorobutanol → (1,1,1-Trichloro-2-methyl-2-propyl) methacrylate

HRID 591117

反応式

HRID 591117 の反応式
[Cl:1][C:2]([Cl:8])([Cl:7])[C:3]([CH3:6])([OH:5])[CH3:4].[Cl:9][C:10]([CH3:16])([CH3:15])[C:11](OC)=[O:12]>>[C:11]([O:5][C:3]([CH3:6])([CH3:4])[C:2]([Cl:8])([Cl:7])[Cl:1])(=[O:12])[C:10]([CH3:16])=[CH2:15].[Cl:9][C:10]([CH3:16])([CH3:15])[C:11]([O:5][C:3]([CH3:6])([CH3:4])[C:2]([Cl:8])([Cl:7])[Cl:1])=[O:12]

参加物

4

反応物 2

HCID 5977ChlorobutanolHCID 211144Methyl 2-chloro-2-methylpropanoate

生成物 2

HCID 118163057(1,1,1-Trichloro-2-methyl-2-propyl) methacrylateHCID 118163068(1,1,1-Trichloro-2-methyl-2-propyl) 2-chloro-2-methylpropanoate

実験手順

An analysis of the crude reaction solution by gas chromatography revealed that the conversion of 1,1,1-trichloro-2-methyl-2-propanol was 67.7% and the yield of methyl 2-chloro-2-methylpropanoate was 36.5%. As to other products, it was obtained (1,1,1-trichloro-2-methyl-2-propyl) methacrylate in a 10.5% yield, and (1,1,1-trichloro-2-methyl-2-propyl) 2-chloro-2-methylpropanoate in a 13.5% yield. The crude reaction solution obtained was distilled under a reduced pressure, thereby obtaining methyl 2-chloro-2-methylpropanoate at a purity of 85%.

後処理

  1. customAn analysis of the crude reaction solution by gas chromatography

出典と根拠

ORDレコード
ord-99ff999dfd8a441e91f4d67f5507c84c
出典データセット
uspto-grants-2016_01
特許番号
US09238612B2

関連ノート

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