関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | 8-Chloro-4-(chloromethyl)-7-hydroxy-2H-chromen-2-one | HCID 89767929 | — |
| 溶媒 | Hydrochloric Acid | HCID 313 | — |
| 生成物 | (7-Chloro-6-hydroxy-1-benzofuran-3-yl)acetic acid | HCID 89767735 | — |
反応手順
A mixture of 1N NaOH (56.7 mL) and 8-chloro-4-(chloromethyl)-7-hydroxy-2H-chromen-2-one (2.78 g) was stirred at 100° C. for 1 h. After cooling, the reaction mixture was acidified with 6N HCl (10 mL). The precipitate was collected by filtration to give the title compound (1.65 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US09238639B2 |
|---|
| 出典データセット | uspto-grants-2016_01 |
|---|
| ORD ID | ord-9cb8e4a309144364acb0d39132346473 |
|---|
| 出典メモ | uspto-grants-2016_01 |
|---|
