化工社化工社 化学情報印刷レポート · 研究参考用
Oxalyl chloride → 2-Chloro-6-fluorobenzoyl isocyanate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Oxalyl chloride | HCID 65578 | — |
| 反応物 | 2-Chloro-6-fluorobenzamide | HCID 98564 | — |
| 溶媒 | 1,2-Dichloroethane | HCID 11 | — |
| 生成物 | 2-Chloro-6-fluorobenzoyl isocyanate | HCID 13051731 | 91,106.602% |
反応手順
To a solution of 2-chloro-6-fluorobenzamide (2.0 g, 0.011 mmol) in EDC (10 mL) was added oxalyl chloride (2.18 g, 0.017 mmol). The reaction mass was refluxed for 24 h. Excess of solvent was removed under vacuum to afford 2.0 g of desired product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09439890B2 |
| 出典データセット | uspto-grants-2016_09 |
| ORD ID | ord-4548ea085f674a4d899d467001b5b831 |
| 出典メモ | uspto-grants-2016_09 |