化工社化工社 化学情報印刷レポート · 研究参考用
1,2-Dichlorobenzene → 3,5-Diallyl-4-hydroxybenzoic acid methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,2-Dichlorobenzene | HCID 7239 | — |
| 反応物 | Ethyl Acetate | HCID 8857 | — |
| 反応物 | 4-Allyloxy-3-allylbenzoic acid methyl ester | HCID 11241748 | — |
| 溶媒 | Hexane | HCID 8058 | — |
| 生成物 | 3,5-Diallyl-4-hydroxybenzoic acid methyl ester | HCID 19385619 | 97% |
反応手順
The product of Step A (3.2 g, 13.8 mmol) was refluxed in 1,2-dichlorobenzene for 3 days in the presence of a catalytic amount of BHT (10 mg). Flash column chromatography of the mixture using hexane and then 10% and 20% ethyl acetate in hexane afforded 3.1 g (97%) of the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05246944 |
| 出典データセット | uspto-grants-1993_09 |
| ORD ID | ord-3170c5d6164841af935791c864839bf7 |
| 出典メモ | uspto-grants-1993_09 |