化工社化工社 化学情報印刷レポート · 研究参考用
Ammonia → 4-Iodobenzoyl isocyanate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ammonia | HCID 222 | — |
| 反応物 | Dichloromethane | HCID 6344 | — |
| 反応物 | 4-Iodobenzoic acid | HCID 12085 | — |
| 反応物 | Oxalyl chloride | HCID 65578 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 4-Iodobenzoyl isocyanate | HCID 14913740 | — |
反応手順
The title compound was prepared according to the procedures described in step-2 and step-3 of Intermediate-26 by using 4-iodo benzoic acid (2.0 g), oxalyl chloride (1.0 ml), ammonia gas, DCM (20 mL), THF (20 mL) to afford 1.5 g of the desired product. 1H NMR (400 MHz, DMSO d6): δ 7.17 (br s, 1H), 7.64 (d, 2H), 8.01 (s, 2H); MS (m/z): 461.14 (M+H)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09439890B2 |
| 出典データセット | uspto-grants-2016_09 |
| ORD ID | ord-c2114230e7974a47b00e7b91356fcf1c |
| 出典メモ | uspto-grants-2016_09 |