戻る
化工社化工社 化学情報印刷レポート · 研究参考用
HRID 594444作成日：2026年10月26日

1-Phenyl-1H-pyrazole-4-carbaldehyde → 6-(2,6-dimethoxyphenyl)-1-((1-phenyl-1H-pyrazol-4-yl)methyl)piperidin-2-one

https://huagongshe.com/reaction/594444

反応式

関与物質

役割名称HCID仕込み量
反応物1-Phenyl-1H-pyrazole-4-carbaldehydeHCID 952089—
反応物Methyl 5-amino-5-(2,6-dimethoxyphenyl)pentanoateHCID 69082713—
生成物6-(2,6-dimethoxyphenyl)-1-((1-phenyl-1H-pyrazol-4-yl)methyl)piperidin-2-oneHCID 69082198—

反応手順

Prepared according to the described general procedure 1 (GP1) by reaction of methyl 5-amino-5-(2,6-dimethoxyphenyl)pentanoate with commercially available 1-phenyl-1H-pyrazole-4-carbaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.80 min.; [M+H]+: 392.36 g/mol.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US09242970B2
出典データセットuspto-grants-2016_01
ORD IDord-2bdb7a61a138445787b4670a75bdc984
出典メモuspto-grants-2016_01