化工社化工社 化学情報印刷レポート · 研究参考用
2-Naphthalenecarboxaldehyde → 5-(2,6-Dimethoxyphenyl)-1-(naphthalen-2-ylmethyl)pyrrolidin-2-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Naphthalenecarboxaldehyde | HCID 6201 | — |
| 反応物 | Methyl 4-amino-4-(2,6-dimethoxyphenyl)butanoate | HCID 69082397 | — |
| 生成物 | 5-(2,6-Dimethoxyphenyl)-1-(naphthalen-2-ylmethyl)pyrrolidin-2-one | HCID 69080985 | — |
反応手順
Prepared according to the described general procedure 1 (GP1) by reaction of methyl 4-amino-4-(2,6-dimethoxyphenyl)butanoate with commercially available 2-naphthaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.87 min.; [M+H]+: 362.35 g/mol.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09242970B2 |
| 出典データセット | uspto-grants-2016_01 |
| ORD ID | ord-d64a509b9b0f4340984d3456ad28f705 |
| 出典メモ | uspto-grants-2016_01 |