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2,6-Dimethoxybenzaldehyde → 6-(2,6-dimethoxyphenyl)-1-((1-methyl-1H-indol-5-yl)methyl)piperidin-2-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,6-Dimethoxybenzaldehyde | HCID 96404 | — |
| 反応物 | (1-methyl-1H-indol-5-yl)methylamine | HCID 18525752 | — |
| 生成物 | 6-(2,6-dimethoxyphenyl)-1-((1-methyl-1H-indol-5-yl)methyl)piperidin-2-one | HCID 69085388 | — |
反応手順
Prepared according to the described general procedure 6 (GP6) with commercially available (1-methyl-1H-indol-5-yl)methanamine and commercially available 2,6-dimethoxybenzaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions E): tR=0.76 min.; [M+H]+: 379.12 g/mol.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09242970B2 |
| 出典データセット | uspto-grants-2016_01 |
| ORD ID | ord-1af8e1f89f8145c9b2340777f6dfc956 |
| 出典メモ | uspto-grants-2016_01 |